TNPG 2005 Pathology

PATHOLOGY

1) Howell Jolly bodies are commonly seen in

a. Megaloblastic Anemia

b. Sickle cell anemia

c. Iron deficiency anemia

d. After splenectomy

Answer : d) After Splenectomy

Reference: Harrison 15^th Edition Chapter 116

2) Most specifice antibody for SLE

a. Anti dsDNA

b. SS-A (Ro)

c. SS-B (La)

d. Anticentromere

Answer : a) Anti ds DNA

Reference: Harrison 16th Edition Pages 317, 1979 and Robbins 7th Edition Page 229

3) All of the following malignancies are associated with HIV except

a. Kaposi’s sarcoma

b. Primary Brain lymphoma

c. primary effusion lymphoma

d. Astrocytoma

Answer : d) Astrocytoma

Reference: Robbins 7^th Edition Page 255

4) Burkitts’ lymphoma chromosome

a. t(8,14)

b. t(9,22)

c. t(1,14)

d. t(2,16)

Answer : A) T(8,14)

Reference: Robbins 7^th Edition Page 671

5) Philadelphia chromosome seen in

a. CML

b. CLL

c. AML

d. ALL

Answer : A) CML

Reference: Robbins 7^th Edition Page 697

6) MacCallum’s plaques are seen in

a. Right Atrium

b. Left Atrium

c. Right Ventricle

d. Left Ventricle

Answer : b) Left Atrium

Reference: Robbins 7^th Edition Page

7) Libman Sack’s endocarditis seen in

a. SLE

b. Rheumatic Fever

c. Both

d. None

Answer : a) SLE

Reference: Robbins 7^th Edition Page 597

8) Irreversible cell injury is seen in

a. Apoptosis

b. Hypertrophy

c. Hyaline change

d. Fatty change

Answer : Apoptosis

Reference: Robbins 7^th Edition Page 26

9) Apoptosis is

a. Programmed cell death

b. Increase in number of cells

c. Increase in bulk of cells

d. None of the above

Answer : a) Programmed cell death

Reference: Robbins 7^th Edition Page 26

10) Hypertrophy of muscle is due to

a. Increase in number of mitochodnria

b. Increase in size of mitochondria

c. Decrease in number of mitochodria

d. Abnormal shape of mitochondria

Answer : a) Increase in number of mitochondria

Reference: Robbins 7^th Edition Page 33

11) Primary amyloidosis is least common in

a. GIT

b. Heart

c. Liver

d. Peripheral nerve

Answer : c) Liver

Reference: Harrison 15^th Edition Page 319

12) Heart failure cells are seen in

a. Chronic Venous congestion of Lung

b. Chronic Venous congestion of Liver

c. After infarction in Myocardium

d. Aorta

Answer : a) Chronic Venous Congestion of Lung

Reference: Robbins 7^th Edition Page 122

13) Which of the following Not a feature of McCune Albright syndrome

a. Precocious puberty

b. Pigmentation

c. Osteogenesis imperfecta

d. Polyostotic fibrous dysplasis

Answer : c) Osteogenesis Imperfecta

Reference: Robbins 7^th Edition Page 1300

14) Kartagener’s syndrome includes all except

a. Sinusitis

b. Dextrocardia

c. Bronchectasis

d. Dysphagia

Answer : d) Dysphagia

Reference: Harrison 15^th Edition Chapter 256

15) Hematuria, hypertension, edema and oliguira are features of

a. Nephrotic syndrome

b. Nephritic syndrome

c. Both

d. None

Answer : Nephritic Syndrome

Reference: Robbins 7^th Edition Page 974

16) Commonest tumor suppressor gene to be involved in humans is

a. p53

b. Rb

c. NF-2

d. NF -1

Answer : a) p53

Reference: Robbins 7^th Edition Page 302

17) Most Common Congenital Heart Disease

a. VSD

b. ASD

c. PDA

d. Co arctation of AortaC

Answer : a) VSD

Reference: Robbins 7^th Edition Page 568

18) Chromosomal disorder which is Not X Linked is

a. XXX syndrome

b. Turner’s syndrome

c. Klinefelter’s syndrome

d. cri du chat syndrome

Answer : c) Criduchat

Reference: Robbins 7^th Edition Page 177

19) Wilson’s chromosome

a. 18

b. 5

c. 13

d. 21

Answer : c) 13

Reference: Robbins 7^th Edition Page 910

20) Hair on end appearance

a. Thalassemia

b. Flourosis

c. Osteosarcoma

d. Pathological fracture

Answer : a) Thalassemia

Reference: Robbins 7^th Edition Page 634