TNPG 2005 Pharmacology

PHARMACOLOGY

1) Actions of opiates in man are all except

a. Constipation

b. Mydriasios

c. Vomiting

d. Analgesia

Answer : b) Mydriasis

Reference: Tripathi 5^th Edition Page 421

2) Drug of choice for Prophylaxis of meningococcal meningitis is

a. Rifampicin

b. Penicillin

c. Erythromycin

d. Septran

Answer : a) Rifampicin

Reference: Tripathi 5^th Edition Page 701

3) Gray Baby syndrome is caused by

a. Chloramphenicol

b. Cycloserin

c. Kanamycin

d. Thioacetazone

Answer : a) Chloramphenicol

Reference: Tripathi 5^th Edition Page 675

4) Which of the following is a Cholestatic drug

a. Erythromycin

b. Phenothiazines

c. Oral Contraceptives

d. All of the above

Answer : d) All of the above

Reference: Harrison 15^th Edition Page 434

5) Ceftriaxone is

a. II Generation short acting

b. III generation long acting

c. active against beta lactamase

d. IV generation used orally

Answer : b) III Generation Long Acting

Reference: Tripathi 5^th Edition Page 665

6) Treatment of bacterial vaginosis. Drug of choice is

a. Ampicillin

b. Metronidazole

c. Ciprofloxacin

d. Fluconazole

Answer : Metronidazole

Reference: Dutta Gynaec 2^nd Edition Page 151

7) Bioavailability is defined as

a. The percentage of drug that is detected in the systemic circulation after its administration

b. The volume of plasma completely cleared of a specific compound per unit time and measured as a test of kidney function.

c. Both

d. None

Answer : The percentage of drug that is detected in the systemic circulation after its administration

Reference: Tripathi 5^th Edition Page 15

8) Which of the following is a Prodrug

a. Enalapril

b. Dopamine

c. AMpicillin

d. Prednisolone

Answer d) Enalapril:

Reference: Tripathi 5^th Edition Page 20

9) Cyclosporine side effect all except

a. Post-transplant lymphoproliferative disorders (PTLDs),

b. nephrotoxicity

c. tremors

d. Hypotension

Answer : d) Hypotension

Reference: Tripathi 5^th Edition Page 788

10) True about Sumatriptan

a. Antagonist of Serotonin

b. Interacts with alpha and beta adrenergic receptors

c. Has antimigranic activity

d. Can be used in a patient with Ischemic Heart disease

Answer : Has antimigranic activity

Reference: Tripathi 5^th Edition Page 153

11) Anticholine esterase with effect on CNS

a. Physostigmine

b. Neostigmine

c. Dacrine

d. Edrophonium

Answer :

Reference: Tripathi 5^th Edition Page

12) DOC for Herpes

a. Acyclovir

b. Zidovudine

c. Indinavir

d. Ribavarin

Answer : a) Acyclovir

Reference: Tripathi 5^th Edition Page 726