044. Which type of RNA has the highest percentage of modified base:
1. mRNA
2. tRNA
3. rRNA
4. snRNA
Answer
3. rRNA
Reference:
Harper 26th Edition Page 356
Chaterjee 6th Edition Page 222 Table 16.3
Quality
Reader
Status
New
QTDF
Most books
Discussion
Ä The tRNAs contain many modifications of the standard bases A,U,G and C, including methyaltion, reduction, deamination and rearranged glycosidic bonds.
Ä Further modification of the tRNA molecules includes nucleotide alkylations and the attachment of the characteristic CpCpAOH terminal at the 3’ end of the molecule by the enzyme nucleotidyl transferase
Explanation
Self Explanatory
Comments
Though it is given in books that tRNA has more number of modified bases than mRNA or rRNA, we have no specific information about bases in the snRNA
Tips
Consider this answer with the proverbial “pinch of salt”
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