DOC for pregnant woman in 2nd trimester with pustular psoriasis Prednisolone

Question 59

DOC for pregnant woman in 2nd trimester with pustular psoriasis

a.       Prednisolone

b.      Dapsone

c.       Acitretin

d.      Methotrexate

Answer

a. Prednisolone

Reference :

Rook 6^th Edition Chapter 35

QTDF

Rook

Quality

Reader

Status

Repeat

Discussion

Cytotoxic drugs, etretinate and PUVA cannot be used in GPP of pregnancy unless termination has become inevitable. Fulminating disease in pregnancy is best treated with prednisolone, the drug which carries the least hazard for the fetus, but methotrexate, retinoids, PUVA or combination therapy may be needed after delivery to allow weaning off the steroid.

Explanation

Self Explanatory : Based on Rook’s Text Book of dermatology

Comments

I have based my answer on the basis of Rook’s Text book of Surgery.

Any doubting Thomas who wants to Rook to see the answer for himself/ herself, can use the following guide to reach the correct page

Psoriasis à Pustular forms of Psoriasis à Generalised Pustular Psoriasis à Localised forms of GPP à Managementà Systemic Therapy

Tips

This was the question asked in AIPG 2005

The only definite indication for giving systemic corticosteroids in pustular psoriasis is:

1.         Psoriatic erythroderma with pregnancy.

2.         Psoriasis in a patient with alcoholic cirrhosis.

3.         Moderate arthritis.

4.         Extensive lesions.